Ekuol

Ekuol (4',7-izoflavandiol), bağırsaklardaki bakteri florası tarafından soya fasulyesi ve diğer bitki kaynaklarında bulunan bir tür izoflavon olan daidzeinden metabolize edilen bir izoflavdiol^[1] östrojendir.^[2]^[3] Estradiol gibi endojen östrojenik hormonlar steroid iken, ekuol steroidal olmayan bir östrojendir. İnsanların yalnızca %30-50'sinde ekuol yapan bağırsak bakterileri bulunur.^[4]

Kaynakça

^ The structures of 7,4’-dihydroxy-isoflavan and its precursors is shown in Structural Elucidation of Hydroxylated Metabolites of the Isoflavan Equol by GC/MS and HPLC/MS 5 Eylül 2008 tarihinde Wayback Machine sitesinde arşivlendi. by Corinna E. Rüfer, Hansruedi Glatt, and Sabine E. Kulling in Drug Metabolism and Disposition (2005, electronic publication).
^ "Enantioselective synthesis of S-equol from dihydrodaidzein by a newly isolated anaerobic human intestinal bacterium". Appl. Environ. Microbiol. 71 (1): 214-9. January 2005. doi:10.1128/AEM.71.1.214-219.2005. PMC 544246 $2. PMID 15640190.
^ Ju, Young H; Sheng, Shubin; Williams, Lee D; Doerge, Daniel R; Katzenellenbogen, Benita S; Helferich, William G; Katzenellenbogen, John A (2004). "Equol, a natural estrogenic metabolite from soy isoflavones". Bioorganic & Medicinal Chemistry. 12 (6): 1559-1567. doi:10.1016/j.bmc.2003.11.035. ISSN 0968-0896. PMID 15018930. Birden fazla yazar-name-list parameters kullanıldı (yardım); Yazar |ad1= eksik |soyadı1= (yardım)
^ "High concordance of daidzein-metabolizing phenotypes in individuals measured 1 to 3 years apart". Br. J. Nutr. 94 (6): 873-6. Aralık 2005. doi:10.1079/bjn20051565. PMID 16351761.

[structure-1] The structures of 7,4’-dihydroxy-isoflavan and its precursors is shown in Structural Elucidation of Hydroxylated Metabolites of the Isoflavan Equol by GC/MS and HPLC/MS 5 Eylül 2008 tarihinde Wayback Machine sitesinde arşivlendi. by Corinna E. Rüfer, Hansruedi Glatt, and Sabine E. Kulling in Drug Metabolism and Disposition (2005, electronic publication).

[bacteria-2] "Enantioselective synthesis of S-equol from dihydrodaidzein by a newly isolated anaerobic human intestinal bacterium". Appl. Environ. Microbiol. 71 (1): 214-9. January 2005. doi:10.1128/AEM.71.1.214-219.2005. PMC 544246 $2. PMID 15640190.

[MuthyalaJu2004-3] Ju, Young H; Sheng, Shubin; Williams, Lee D; Doerge, Daniel R; Katzenellenbogen, Benita S; Helferich, William G; Katzenellenbogen, John A (2004). "Equol, a natural estrogenic metabolite from soy isoflavones". Bioorganic & Medicinal Chemistry. 12 (6): 1559-1567. doi:10.1016/j.bmc.2003.11.035. ISSN 0968-0896. PMID 15018930. Birden fazla yazar-name-list parameters kullanıldı (yardım); Yazar |ad1= eksik |soyadı1= (yardım)

[percent-4] "High concordance of daidzein-metabolizing phenotypes in individuals measured 1 to 3 years apart". Br. J. Nutr. 94 (6): 873-6. Aralık 2005. doi:10.1079/bjn20051565. PMID 16351761.

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